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Key Words
- Active Immunity - production of antibodies during immune response
- Agglutinate - clumping of antigens called by antibodies (Igs)
- Allergy - inappropriate responses to certain foods and pollens that causes immune response
- Aorta - largest blood vessel
- Aortic Loops - 5 pairs of vessels that act as an additional blood pump in earthworms
- Arteries - branched off of Aorta
- Arterioles - branched off of arteries
- Antigen - non-self entities like bacteria, toxins, foreign blood cells, etc
- B cells - produces antibodies
- Blood - 4-6 liters in human body. 55% liquid (plasma), 45% cellular component
- Capillaries - branched off of arterioles
- Coronary Sinus - deoxygenated blood from heart muscles
- Erythroblastosis fetalis - caused by Rh factor. Mother has immune response to fetal blood
- Fibrin - comes from fibrinogen, comes in threads and would trap blood cells to form clot
- Fibrinogen - converted into fibrin by thrombin
- Granulocytes - inflammatory response that phagocytize antigenic material
- Humoral immunity - production of antibodies against antigens
- Immunoglobulins - large proteins that recognize and bind to specific antigen for removal
- Inferior Vena Cava - deoxygenated blood from the lower half of the blood
- Interferons - proteins produced by cell under viral attack that diffuse and help other cells
- Left Atrium - receives blood from the 4 pulmonary veins (2 from each lung). Pumps blood through mitral valve
- Left Ventricle - receives blood from the left atrium, through the mitral valve, and pumps blood through the semi-lunar valves of aorta to the rest of the body
- Leukocytes - white blood cells, phagocytic. Larger than erythrocytes
- Lung Pathway - nose > pharynx > larynx > trachea > bronchi > bronchioles > alveoli
- Lymph - interstitial fluid
- Lymph nodes - swellings along lymph vessels containing leukocytes that filter the lymph, removing and destroying foreign particles and pathogens
- Mitral valve - the door between left atrium and left ventricle (bicuspid)
- Passive Immunity - transfer of antibodies from another individual or organism, short lasting
- Plasma - 55% of blood - nutrients, salts, gasses, wastes, hormones, blood proteins
- Platelets - cell fragments that lack nuclei and involved in clot formation
- Prothrombin - activated by thromboplastin into thrombin, made in liver
- Pulmonary Circulation - toward the lung to oxygenate the blood
- Right Atrium - receives the deoxygenated blood through 3 sources
- Right ventricle - receives blood from the right atrium through the right-atrio-ventricular opening. Pumps blood out to the pulmonary artery through the semi-lunar valves of pulmonary artery
- Semi-lunar valves - valves to prevent backflow into the left or right ventricles
- Sinus - a location for open circulatory system to exchange nutrients and wastes (arthropods)
- Superior Vena Cava - deoxygenated blood from the arm, thorax, and head region
- Systemic Circulation - pumping oxygenated blood throughout the body
- T Cells - cytolysis of infected cells
- Thrombin - activated form of prothrombin, converts fibrinogen into fibrin
- Thromboplastin - clotting factor that interacts with prothrombin, activating it
- Vaccination - individual injected with another form of antigen and antibodies build up
- Vein - Converged from venules
- Venules - converged from capillaries
Plants
- Cambium cells - two layers thick and differentiates into xylem or phloem. Lateral meristem
- Companion Cells - a type of phloem cell
- Capillary Action - water in narrow space naturally goes up due to hydrogen-bond properties
- Fibrovascular bundle - runs up and down stem, contains xylem, phloem, and cambium cells
- Heartwood - inner layer of xylem that's dead and can be used for lumber
- Meristem - actively dividing, undifferentiated cells of a plant
- Phloem - thin-walled cells that transport nutrients down the stem
- Pith - the innermost layer, involved in storage of nutrients and plant support
- Root - absorbs materials and anchor the plant. Apical meristem at the tip
- Root hair - increases surface area for absorption of water and mineral
- Root pressure - water entering root hair exerts pressure which pushes water up
- Sapwood - outer layer of xylem that's alive
- Sieve tube cells - a type of phloem cell
- Stem - primary organ of transport
- Tracheids - a type of xylem cell
- Translocation - circulation
- Transpiration - water evaporate from leaves, creating vacuum that sucks up water from stem
- Vessel Cell - a type of xylem cell
Circulation in Invertebrates
- Protozoans
- Diffusion within the cell
- Cnidarians
- Hydra and other cnidarians only have cell wall as thick as 2 cells, so any cell is in direct contact with internal or external environment
- Arthropods (insects, crustacean, arachnids, myriapods)
- Open circulatory system
- Blood (interstitial fluid) is in direct contact with the body tissues
- Flow of blood via body movement
- The exchange happens in the "sinus" and the blood flows through the dorsal vessel into these sinus
- Annelids (earthworms)
- Closed circulator system
- Blood confined in blood vessels
- Blood moved toward the head via the dorsal vessels via coordinated contractions
- Aortic loops connects the dorsal vessel to the ventral vessel and functions as additional pump
- No red blood cell, but does have hemoglobin-like pigments
Circulation in Humans
- General
- Composed of
- a heart with 4 chambers
- Blood vessels
- Blood
- Blood pumped through aorta (going away from heart)
- Blood returns through vein (coming to heart)
- Blood vessel branching
- Aorta branches off into series of arteries
- Arteries branches off into arterioles
- Arterioles branches off into microscopic capillaries
- Capillaries converges into venules
- Venules converges into veins
- Exchange happens through the capillaries via diffusion
- The Heart
- The right side
- Responsible for oxygenating the blood, this is called pulmonary circulation
- Right Atrium
- Thin walled
- Receives the deoxygenated blood from 3 sources
- Superior vena cava - from head, arms, and thorax
- Inferior vena cava - lower parts of the body
- Coronary sinus - blood from walls of the heart
- Right ventricle
- Muscular
- Receives blood from the right atrium
- Through the right atrio-ventricular opening
- Pumps the blood through pulmonary arteries to the lungs
- The opening of this is guarded by a tri-cuspid valve called "semi-lunar valves of pulmonary artery"
- When the ventricle contracts, the semi-lunar valve closes and blood is forced past through the pulmonary artery
- The left side
- Responsible for circulation of oxygenated blood, this is called systemic circulation
- Left Atrium
- Thin walled
- Receives oxygenated blood from the lung via 4 pulmonary veins
- Pumps the blood through mitral valve to the left ventricle
- Left ventricle
- Extremely muscular
- Receives blood from left atrium through the mitral valve
- Pumps oxygenated blood to the rest of the body through aorta and the semi-lunar valve of aorta
- Blood Vessels
- Three types of blood vessels
- Arteries
- Thick-walled, muscular, elastic
- Transports blood away from the heart
- Veins
- Thin-walled, inelastic
- Transport blood to the heart
- Blood flow depends on compression by skeletal muscles during movement
- Larger veins have valves that prevent backflow
- Capillaries
- Very thin walls composed of a single layer of endothelial cells
- Gas, nutrient, enzymes, hormones, wastes can readily diffuse
- Red blood cells must often pass through them single file
- Lymph vessels
- Called the secondary circulatory system
- Transports excess interstitial fluid called lymph
- Lymph nodes are swellings along lymph vessels containing white blood cells that filter the lymph and destroy foreign particles
- It also absorbs chylomicrons from small intestine and deliver them to the cardiovascular circulation
- Blood
- General
- On average, human body contains 4-6 liters of blood
- Blood consist of 55% liquid and 45% cellular components
- Plasma is the liquid portion
- Consists of salts, nutrients, respiratory gases, wastes, hormones, blood proteins
- Cellular components
- Erythrocytes (red blood cell)
- Leukocytes (white blood cell)
- Platelets
- Erythrocytes (red blood cell)
- One cell contains approximately 250 million molecules of hemoglobin
- When hemoglobin binds oxygen, it's called oxyhemoglobin
- Formed by stem cells in the bone marrow where they lose nuclei, mitochondria, and membranous organelles
- Lives for about 120 days
- Phagocytized by special cells in spleen and liver
- Leukocytes (white blood cell)
- Larger than erythrocytes
- Phagocytize foreign matter and organisms such as bacteria
- Some migrate from blood to tissues where they mature into stationary cells called macrophages
- Lymphocytes - involved in immune response and production of antibodies or cytolysis of infected cells
- B cells - produces antibodies
- T cells - cytolysis of infected cells
- Platelets - cell fragments that lack nuclei and involved in clot formation
Functions of the Circulatory System
- Transport of gases
- Hemoglobin transports O2 and CO2
- Transport of nutrients and wastes
- Amino acids and simple sugars
- Are absorbed into the bloodstream at the intestine
- After processing, delivered to the rest of the body
- Waste products
- Diffuse into capillaries
- Delivered to appropriate excretory organs
- Clotting
- Steps for clotting
- Platelets meet exposed collagen of damaged vessel
- Release a chemical that causes neighboring platelets to stick together
- Forms a platelet plug
- Both platelets and damage tissues releases thromboplastin
- Thromboplastin is a clotting factor
- Thromboplastin with calcium and vitamin K, converts prothrombin to active thrombin
- The active thrombin would convert fibrinogen into fibrin
- Fibrin would form threads into a coat to stop the flow of blood to form clot
- Immunological Reactions
- The body can distinguish between "self" and "nonself" and remember the non-self that it has encountered before
- The immune system is two different mechanisms
- Lymphocytes are responsible for
- Humoral immunity
- Produces antibodies
- Cell-mediated immunity
- Cells that combat fungal and viral infection
- Immune Cell types
- B cells - produces antibodies
- Cytotoxic T cells - destroy infected cell
- Suppressor T cells - regulates activity of B and T cells
- Helper T cells - activate B and T cells
- Humoral immunity
- Produces antibodies and very specific to the antigens
- Antibodies are also called immunoglobulins (Igs)
- Recognize and bind to specific antigen
- Calls for white blood cells (leukocytes) to phagocytize the antigen
- Causes antigens to clump together into large insoluble complex
- This clumping is called agglutinate
- Active immunity
- Production of antibodies during immune response
- Can be given with vaccination
- Individual is injected with weakened, inactive form of the antigen and this stimulates the body to produce specific antibodies against it
- Passive immunity
- Only last as long as the antibodies circulate in the blood system
- Transfer of antibodies from another individual or organism
- ie - maternal antibodies cross the placenta and enters fetal circulation
- Gamma globulin - contains wide variety of antibodies
- Nonspecific Defense Mechanism
- Skin
- physical barrier against bacterial invasion
- Sweat attacks bacterial cell wall
- Mucous-coated epithelia
- Lines passages like respiratory
- Filter and trap foreign particles
- Macrophages
- Engulf and destroy foreign particle
- Inflammatory
- Initiated by the body in response to physical damage
- Histamine is what causes the inflammation
- Blood vessels dilate and increase blood flow
- Granulocytes
- Attracted to injury site and phagocytize antigenic material
- Often fever accompanies such
- Interferons
- Proteins produced by cells under viral attack
- Diffuse to other cells and prevent the spread of virus
- Allergy
- Inappropriate response to foods and pollens that causes the body to form antibodies and release histamine
- Rejection of Transplants
- Immune response to foreign organs or tissues causing transplant to be rejected
- Immuno-suppressing drugs can be used to lower the immune response
- Blood
- Red blood cells have characteristic cell-surface proteins (antigens)
- ABO Group
- Blood type A has A Antigen and produces anti-B antibodies
- Blood type B has B antigen and produces anti-A antibodies
- AB (universal recipient), has A and B antigen, produces no antibodies
- O (universal donor), has no antigen, produces anti-A and anti-B
- Rh factor
- Rh+ - possesses Rh antigen
- Rh- - lacking the Rh antigen
- Rh- woman with Rh+ fetus has an immune response. The next time she carries a Rh+ fetus, the blood that goes into fetal circulation will destroy fetal red blood cell
- This causes erythroblastosis fetalis
Transport Systems in Plants
- General
- Circulation is called "translocation"
- Stem is the primary organ of transport
- Fibrovascular bundles - run up and down the stem
- Contains xylem, phloem, and cambium cells
- Xylem
- Cells
- Thick-walled
- Hollow
- Located on the inside of the vascular bundle
- Two types of Xylem Cells
- Vessel cells
- Tracheids
- Carries water and minerals up the plant and give the plant the rigid suport
- When older xylem cells die, they form heartwood (lumber)
- The living portion is called sapwood
- How water is pulled up through the xylem cells
- Transpiration pull - as water evaporates from the leaves of plants, vacuum is created which pulls up the water from stem
- Capillary action - any liquid in a thin tube will rise due to surface tension and the interactions between liquid and the tube
- Root Pressure - water going into root hairs exert pressure which push water up
- Phloem
- Thin-walled cells on the outside of the vascular bundle
- Transports nutrients down the stem
- Two types of phloem cells
- Sieve tube cells
- Companion cells
- If a stripe of bark around the trunk is removed (girdled), the tree will die
- Cambium
- Two layers thick
- Divide and differentiates into either xylem or phloem
- This differentiation depends on if it's closer to xylem or phloem
- Situated between xylem and phloem layer
- Gross structure of a woody stem
- Epidermis (outerbark) > cortex > phloem > cambium, xylem > pith
- Pith is involved in the storage of nutrients and plant support
- Root
- Function
- Absorb material through root hairs
- Anchor plants
- Provide storage
- Root hairs
- Specialized cells of the root to increase surface area for absorption of water and mineral
- Regions of Growth in the Plant
- Meristem - active dividing undifferentiated cells of a plant
- Cambium - lateral meristem
- Apical meristem - tip of roots and stems for elongation
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